Accelerated onset of rocuronium

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Effect of Ephedrine on Onset of Action of Rocuronium

The purpose of this study is to assess the effects of ephedrine on onset time of rocuronium, by comparing onset time when using rocuronium alone and with priming with rocuronium. In this randomized clinical trial, 120 patients with the American Anesthesiologists Society (ASA) class I/II who required laryngoscopy and tracheal intubation for elective surgery were assigned to 4 groups. Priming dos...

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The effect of phenylephrine on the onset time of rocuronium

BACKGROUND Several studies have demonstrated that ephedrine shortens the onset time of muscle relaxants, and it does so probably by increasing the cardiac output. However, elevation of the systemic blood pressure through α adrenergic stimulation via ephedrine may affect the onset of muscle relaxants during the induction of anesthesia. We investigated the effect of phenylephrine, which is a sele...

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Onset and Duration of Intravenous and Intraosseous Rocuronium in Swine

INTRODUCTION The intraosseous (IO) route has become a popular method to gain access to the peripheral circulation in emergency situations. Despite little supporting data, it is generally believed that IO absorption is immediate and equivalent to the intravenous (IV) route. It is important to determine if rocuronium can effectively be administered by the IO route. The aim of the study was to det...

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Different priming techniques, including mivacurium, accelerate the onset of rocuronium.

Different priming sequences of equipotent doses of rocuronium and mivacurium on the onset of maximum neuromuscular block and intubating conditions were compared with those obtained after succinylcholine. During thiopentone-fentanylnitrous oxide anaesthesia, 70 patients were randomly assigned into seven groups. Group I received mivacurium 0.15 mg.kg-1 as a single bolus dose. Group II received a ...

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Delayed-onset malignant hyperthermia in association with rocuronium use.

PURPOSE Two cases of malignant hyperthermia suspected to be related to the use of a nondepolarizing neuromuscular blocker are reported. SUMMARY A pharmacogenetic disorder that may occur in as many as 1 in 3000 anesthesia procedures, malignant hyperthermia has been linked to the use of certain anesthetic gases and depolarizing neuromuscular blocking agents (e.g., succinylcholine). Although non...

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ژورنال

عنوان ژورنال: Canadian Journal of Anaesthesia

سال: 1995

ISSN: 0832-610X,1496-8975

DOI: 10.1007/bf03015495